Brain

The Command Center for Performance & Longevity

Brain April 13, 2025 | 8 min

Brain: The Control Center of Your Health

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Derek Nelson

Brain Health

Top Picks

1.

The concept of “Tenacity”; the stimulation and growth of the Anterior Mid-Cingulate Cortex (aMCC). 

Research shows that the anterior mid-cingulate cortex (aMCC)—a small but pivotal area of the brain—is central to what experts call “tenacity,” the drive behind perseverance and determination. Behavioral training techniques can stimulate and even increase the size of the aMCC, potentially enhancing mental resilience and contributing to long-term brain health and longevity. This finding underscores how simple, deliberate actions can lead to meaningful improvements in how we think, act, and age.

2.

Neuroplasticity

Enhancing the structure and function of the aMCC boosts neuroplasticity—improving connectivity, fostering adaptive neural changes, and increasing the density of protein receptors throughout the limbic circuits.

3.

Mental Health

Enhancing this brain region can boost motivation, discipline, and self-confidence in one’s own mental abilities to tackle challenges. Such training not only fortifies the resilience needed to complete difficult tasks but also shows promise in alleviating symptoms of depression, anxiety, dementia, and learning disabilities.

4.

David Goggins and Dr. Andrew Huberman on the Neuroscience of Willpower
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David Goggins—a retired Navy SEAL and ultramarathoner—joins Dr. Andrew Huberman, a true original and thought leader, to explore how pushing through challenges strengthens the anterior midcingulate cortex (aMCC). They reveal that overcoming discomfort builds mental toughness and resilience, driving willpower and performance. Not exactly a deep pick, but it shows why Andrew stands out in this field.

Co-founder, President @ Clay Health & Care

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More questions?

Why is the brain called the "control center" of your health?

Your brain regulates everything from mood and memory to movement, hormones, and even motivation. It orchestrates how you respond to stress, adapt to challenges, and recover—making it the ultimate driver of your overall health and performance.

What role does the anterior mid-cingulate cortex (aMCC) play in motivation and resilience

The aMCC is like your brain’s internal engine for willpower and discipline. It lights up when you push through discomfort or stay focused on long-term goals. Strengthening this area can improve your mental endurance and capacity to face life’s demands.

Can brain structure actually change through habit and training?

Yes—thanks to neuroplasticity, your brain can rewire and strengthen through targeted behaviors. Training your aMCC through consistent challenges, healthy routines, and recovery strategies helps build long-term mental strength and adaptability. The Coaching Team at Clay Health & Care live by this scientific reality and bring that into our clinical programs everyday.

How does Clay Health & Care assess and support brain health in its optimization programs?

At Clay, we measure biomarkers tied to cognitive function, stress, and inflammation, and connect those results to personalized strategies like breath work, sleep optimization, and behavioral training. Because brain health isn’t just mental—it’s metabolic, physical, and foundational to all five Elements of Health.